Ghislain Opdenakker Selected Research

Interleukin-8 (Interleukin 8)

2/2014	The Sputum Colour Chart as a predictor of lung inflammation, proteolysis and damage in non-cystic fibrosis bronchiectasis: a case-control analysis.
7/2010	Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.
9/2008	Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation.
4/2006	Remnant epitopes, autoimmunity and glycosylation.
9/2004	Chemokines and gelatinases in the aqueous humor of patients with active uveitis.
1/2004	The countercurrent principle in invasion and metastasis of cancer cells. Recent insights on the roles of chemokines.
1/2003	The CXC chemokine GCP-2/CXCL6 is predominantly induced in mesenchymal cells by interleukin-1beta and is down-regulated by interferon-gamma: comparison with interleukin-8/CXCL8.

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Ghislain Opdenakker Research Topics

Disease

74	Inflammation (Inflammations) 02/2024 - 01/2002
36	Neoplasms (Cancer) 03/2023 - 07/2002
35	Diabetic Retinopathy (Retinopathy, Diabetic) 10/2023 - 08/2006
22	Epiretinal Membrane (Epiretinal Membranes) 10/2023 - 02/2007
18	Infections 01/2021 - 11/2003
17	Autoimmune Diseases (Autoimmune Disease) 03/2023 - 01/2003
14	Malaria 01/2020 - 05/2010
13	Uveitis 04/2022 - 09/2004
13	Multiple Sclerosis 01/2020 - 01/2003
11	Neoplasm Metastasis (Metastasis) 11/2016 - 07/2002
10	Necrosis 02/2020 - 12/2004
8	Hypoxia (Hypoxemia) 08/2023 - 02/2015
8	Rheumatoid Arthritis 01/2023 - 03/2002
8	Fibrosis (Cirrhosis) 01/2022 - 12/2012
7	Septic Shock (Toxic Shock Syndrome) 10/2017 - 08/2002
6	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 02/2014
6	Cerebral Malaria 11/2019 - 09/2006
6	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2018 - 06/2003
6	Peritonitis 09/2009 - 01/2006
5	Virus Diseases (Viral Diseases) 02/2024 - 06/2003
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 10/2010
5	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 11/2019 - 02/2010
5	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 03/2018 - 05/2010
5	Pancreatic Neoplasms (Pancreatic Cancer) 10/2017 - 01/2016
5	Shock 01/2014 - 08/2002
5	Pancreatitis 04/2009 - 01/2003
4	Arthritis (Polyarthritis) 01/2023 - 01/2006
4	Crohn Disease (Crohn's Disease) 01/2022 - 11/2005
4	Ulcerative Colitis 01/2022 - 07/2014
4	Sarcoidosis (Schaumann Disease) 04/2020 - 01/2016
4	Adenocarcinoma 12/2016 - 07/2010
4	Sepsis (Septicemia) 03/2015 - 08/2002
4	Melanoma (Melanoma, Malignant) 11/2014 - 09/2006
3	Proliferative Vitreoretinopathy 08/2023 - 02/2007
3	Osteoarthritis 01/2023 - 03/2002
3	Wounds and Injuries (Trauma) 01/2023 - 01/2018
3	COVID-19 11/2022 - 11/2020
3	Colitis 01/2018 - 11/2016
3	Chronic Pancreatitis 01/2016 - 05/2003

Drug/Important Bio-Agent (IBA)

68	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2021 - 01/2002
59	Matrix Metalloproteinases (MMPs)IBA 01/2023 - 03/2002
42	ChemokinesIBA 11/2022 - 07/2002
33	EnzymesIBA 01/2023 - 03/2002
30	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2002
27	Peptide Hydrolases (Proteases)FDA Link 02/2024 - 03/2002
27	CytokinesIBA 08/2023 - 05/2004
17	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 07/2010
17	ImmunosorbentsIBA 01/2020 - 09/2004
16	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2013
12	LigandsIBA 10/2023 - 11/2003
12	Metalloproteases (Metalloproteinases)IBA 08/2020 - 09/2006
11	Matrix Metalloproteinase InhibitorsIBA 01/2023 - 06/2003
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 01/2006
8	Retinaldehyde (Retinal)IBA 08/2023 - 02/2015
7	Chemotactic FactorsIBA 11/2022 - 05/2004
7	AutoantibodiesIBA 01/2022 - 12/2004
7	oxyamylose (COAM)IBA 01/2022 - 10/2008
7	AutoantigensIBA 01/2022 - 01/2003
7	CXC ChemokinesIBA 11/2014 - 01/2004
7	Interleukin-8 (Interleukin 8)IBA 02/2014 - 01/2003
6	Peptides (Polypeptides)IBA 01/2022 - 01/2014
6	InterferonsIBA 01/2021 - 06/2003
6	ZymosanIBA 09/2009 - 01/2006
5	cobaltous chloride (cobalt(II)chloride)IBA 08/2023 - 12/2016
5	EpitopesIBA 01/2023 - 03/2002
5	Antiviral Agents (Antivirals)IBA 01/2022 - 10/2008
5	Complement System Proteins (Complement)IBA 01/2021 - 09/2006
5	GelatinIBA 01/2021 - 02/2014
5	Tissue Inhibitor of Metalloproteinase-1IBA 01/2020 - 01/2013
5	hemozoinIBA 01/2014 - 08/2011
4	Protease Inhibitors (Protease Inhibitor)IBA 02/2024 - 02/2016
4	Monoclonal AntibodiesIBA 03/2023 - 01/2014
4	Interleukin-17 (Interleukin 17)IBA 11/2022 - 12/2007
4	GelatinasesIBA 01/2021 - 09/2004
4	Streptozocin (Streptozotocin)FDA Link 01/2021 - 01/2003
4	Infliximab (Remicade)FDA Link 02/2020 - 11/2005
4	Insulin (Novolin)FDA Link 10/2018 - 01/2003
4	progelatinaseIBA 08/2014 - 12/2004
4	Toll-Like Receptors (Toll-Like Receptor)IBA 07/2010 - 11/2003
3	Anti-Bacterial Agents (Antibiotics)IBA 11/2022 - 09/2011
3	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2022 - 11/2019
3	GlycosaminoglycansIBA 01/2022 - 08/2012
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021 - 02/2014
3	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 12/2016
3	AntigensIBA 01/2021 - 01/2019
3	GlucocorticoidsIBA 11/2019 - 01/2016
3	Dexamethasone (Maxidex)FDA LinkGeneric 11/2019 - 05/2010
3	Interleukin-10 (Interleukin 10)IBA 08/2019 - 05/2011
3	InterleukinsIBA 08/2019 - 07/2010
3	ProdrugsIBA 01/2019 - 05/2013
3	pro-matrix metalloproteinase 9IBA 01/2019 - 08/2011
3	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2019 - 03/2009
3	Interleukin-6 (Interleukin 6)IBA 06/2018 - 01/2016
3	EndopeptidasesIBA 01/2018 - 10/2007
3	ZincIBA 01/2018 - 10/2007
3	Dextrans (Dextran)FDA Link 01/2018 - 11/2016
3	Protein Isoforms (Isoforms)IBA 12/2017 - 07/2002
3	Minocycline (Cyclops)FDA LinkGeneric 01/2017 - 06/2003
3	Matrix Metalloproteinase 2 (Gelatinase A)IBA 11/2016 - 03/2004

Therapy/Procedure

20	Therapeutics 03/2023 - 06/2003